Gynecology World Conference 2026

Abstract

Objective: It aims to conduct a systematic review of existing research on the awareness and acceptability of Human Papillomavirus (HPV) DNA testing and cervical cancer screening among pregnant women in Nigeria and to identify the key factors influencing their uptake.

Methods: A narrative literature review was conducted using studies carried out across different regions of Nigeria.

Eligible studies included cross-sectional, descriptive, and quasi-experimental designs focusing on awareness, knowledge, perception, and acceptability of HPV infection, HPV DNA testing, and cervical cancer screening among women, particularly antenatal attendees).

Data from selected studies were synthesized and grouped into key thematic areas, including awareness levels, acceptability, uptake, and associated socio-demographic and health system factors).

Results:The reviewed studies consistently revealed low awareness and limited knowledge of HPV infection, HPV DNA testing, and cervical cancer screening among pregnant women.

However, acceptability of HPV DNA testing and related screening methods was generally high, especially following educational interventions.

Despite this, uptake of screening services remained poor, largely due to barriers such as inadequate health education, financial limitations, fear of adverse effects during pregnancy, cultural influences, and limited access to screening facilities.

Socio-demographic variables, including educational level, income, and prior knowledge of cervical cancer, were significantly associated with awareness and acceptability.

Importantly, interventional studies reported notable improvements in both knowledge and willingness to undergo screening after targeted educational programs.

Conclusion: There is a marked gap between awareness and the actual uptake of HPV DNA testing and cervical cancer screening among pregnant women in Nigeria.

While acceptability tends to be high especially after appropriate education, utilization remains limited due to both systemic and individual constraints.

Integrating HPV DNA testing into routine antenatal care, together with enhanced health education and better access to services, is essential to improve screening uptake and reduce the burden of cervical cancer.